Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 6/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.40 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL710306 | 1.00 | PYCR1 (0.46) | PYCR1MAPTIDO1CYP3A4SMN1; SMN2 | |
| SCHEMBL3634811 | 0.83 | PYCR1 (0.44) | PYCR1MAPTIDO1CYP3A4SMN1; SMN2 | |
| SCHEMBL500015 | 0.82 | CYP3A4 (0.45) | PYCR1MAPTIDO1CYP3A4SMN1; SMN2 | |
| SCHEMBL17410220 | 0.79 | PYCR1 (0.41) | PYCR1MAPTIDO1CYP3A4SMN1; SMN2 | |
| SCHEMBL597241 | 0.79 | MAOA (0.41) | MAPTHTTMEN1KMT2APSEN1 | |
| SCHEMBL596499 | 0.79 | MAOA (0.41) | LMNAPPARASLC6A4 | |
| SCHEMBL29485890 | 0.79 | PYCR1 (0.47) | PYCR1MAPTIDO1CYP3A4SMN1; SMN2 | |
| SCHEMBL26078400 | 0.79 | PYCR1 (0.47) | PYCR1MAPTIDO1CYP3A4SMN1; SMN2 | |
| SCHEMBL979069 | 0.79 | PYCR1 (0.47) | PYCR1MAPTIDO1CYP3A4SMN1; SMN2 | |
| SCHEMBL29493203 | 0.78 | IDO1 (0.50) | MAPTIDO1CYP3A4SMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573096-A1 | INHIBITORS OF MYELOPEROXIDASE | Astrazeneca AB (SE) | 2025-06-25 | — | — | EP | disclosed |
| CN-115066428-B | Boric acid derivatives | 首药控股(北京)股份有限公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-118791498-A | Tetracyclic compound, preparation method thereof and application thereof in medicines | 江苏恒瑞医药股份有限公司 | 2024-10-18 | — | — | CN | disclosed |
| WO-2024038131-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-02-22 | — | — | WO | disclosed |