Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 10/20 | 0.47 |
| ▸ | TPO | P07202 | 4/20 | 0.46 |
| ▸ | PNP | P00491 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27223452 | 1.00 | MPO (0.47) | MPOTPOPNPCYP3A4KCNH2 | |
| SCHEMBL27223531 | 0.87 | MPO (0.59) | MPOTPOCYP3A4KCNH2 | |
| SCHEMBL30749360 | 0.87 | MPO (0.59) | MPOTPOCYP3A4KCNH2 | |
| SCHEMBL30749324 | 0.82 | MPO (0.71) | MPOTPOCYP3A4KCNH2 | |
| SCHEMBL27223485 | 0.76 | SIGMAR1 (0.43) | TMEM97SIGMAR1 | |
| SCHEMBL27224026 | 0.75 | MPO (0.73) | MPOTPOPNPCYP3A4KCNH2 | |
| SCHEMBL30749257 | 0.75 | MPO (0.73) | MPOTPOPNPCYP3A4KCNH2 | |
| SCHEMBL30749232 | 0.75 | RECQL (0.36) | CYP3A4JAK2JAK1TYK2 | |
| SCHEMBL27223628 | 0.75 | RECQL (0.36) | CYP3A4JAK2JAK1TYK2 | |
| SCHEMBL30749340 | 0.72 | MPO (0.49) | MPOTPOTMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573096-A1 | INHIBITORS OF MYELOPEROXIDASE | Astrazeneca AB (SE) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038131-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-02-22 | — | — | WO | disclosed |