Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30805103 | 0.88 | TRPA1 (0.33) | RHEBTRPA1 | |
| SCHEMBL27265131 | 0.88 | TRPA1 (0.33) | RHEBTRPA1 | |
| Iodide SCHEMBL30805022 | 0.87 | — | — | |
| SCHEMBL27283125 | 0.86 | TRPA1 (0.32) | RHEBTRPA1 | |
| SCHEMBL30840249 | 0.86 | TRPA1 (0.32) | RHEBTRPA1 | |
| SCHEMBL30805006 | 0.85 | — | — | |
| SCHEMBL27276374 | 0.85 | — | — | |
| SCHEMBL30840100 | 0.85 | PRKAB2 (0.38) | RHEBTRPA1 | |
| SCHEMBL27283024 | 0.85 | PRKAB2 (0.38) | RHEBTRPA1 | |
| SCHEMBL31111053 | 0.84 | RHEB (0.34) | RHEBTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054851-A1 | MACROCYCLIC COMPOUNDS, COMPOSITIONS AND METHODS OF USING THEREOF | SIONNA THERAPEUTICS (US) | 2024-03-14 | — | — | WO | disclosed |