Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 2/20 | 0.37 |
| ▸ | BTK | Q06187 | 4/20 | 0.37 |
| ▸ | NAMPT | P43490 | 3/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27376827 | 1.00 | SMO (0.37) | SMOBTKNAMPTMETTRPA1 | |
| SCHEMBL31456920 | 0.94 | SMO (0.37) | SMOBTKNAMPTMETMERTK | |
| SCHEMBL27377090 | 0.94 | SMO (0.37) | SMOBTKNAMPTMETMERTK | |
| SCHEMBL31456927 | 0.90 | SMN1; SMN2 (0.39) | SMOBTKNAMPTMERTKSMN1; SMN2 | |
| SCHEMBL27377070 | 0.90 | SMN1; SMN2 (0.39) | SMOBTKNAMPTMERTKSMN1; SMN2 | |
| SCHEMBL30751453 | 0.89 | CCR1 (0.37) | SMOBTKADORA1NR2E3 | |
| SCHEMBL27375170 | 0.88 | MET (0.37) | SMOBTKNAMPTMETTRPA1 | |
| SCHEMBL30751355 | 0.88 | MET (0.37) | SMOBTKNAMPTMETTRPA1 | |
| SCHEMBL31456924 | 0.88 | GRIN2B (0.38) | SMOBTKNAMPTMETMERTK | |
| SCHEMBL27376939 | 0.88 | GRIN2B (0.38) | SMOBTKNAMPTMETMERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119654324-A | Novel compounds as hypoxia inducible factor 1 (HIF-1) inhibitors or Vascular Endothelial Growth Factor (VEGF) inhibitors and pharmaceutical compositions comprising the same | 株式会社次代生物科学 | 2025-03-18 | — | — | CN | claimed |
| CN-119654324-A | Novel compounds as hypoxia inducible factor 1 (HIF-1) inhibitors or Vascular Endothelial Growth Factor (VEGF) inhibitors and pharmaceutical compositions comprising the same | 株式会社次代生物科学 | 2025-03-18 | — | — | CN | disclosed |
| WO-2024030000-A1 | NOVEL COMPOUND AS HYPOXIA-INDUCIBLE FACTOR 1(HIF-1) INHIBITOR OR VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 넥스트젠바이오사이언스 | 2024-02-08 | — | — | WO | disclosed |