Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 3/20 | 0.38 |
| ▸ | MERTK | Q12866 | 7/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | MELK | Q14680 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27377070 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2NAMPTMERTKSMOBTK | |
| SCHEMBL27375170 | 0.92 | MET (0.37) | NAMPTMERTKSMOBTKKIT | |
| SCHEMBL27378439 | 0.92 | MET (0.37) | SMN1; SMN2MERTKSMOBTKKIT | |
| SCHEMBL30751460 | 0.92 | MET (0.37) | SMN1; SMN2MERTKSMOBTKKIT | |
| SCHEMBL30751355 | 0.92 | MET (0.37) | NAMPTMERTKSMOBTKKIT | |
| SCHEMBL30751453 | 0.91 | CCR1 (0.37) | SMOBTKADORA1 | |
| SCHEMBL27376866 | 0.91 | MET (0.37) | NAMPTMERTKSMOBTKKIT | |
| SCHEMBL31456920 | 0.90 | SMO (0.37) | SMN1; SMN2NAMPTMERTKSMOBTK | |
| SCHEMBL30751430 | 0.90 | SMO (0.37) | SMN1; SMN2NAMPTMERTKSMOBTK | |
| SCHEMBL27376827 | 0.90 | SMO (0.37) | SMN1; SMN2NAMPTMERTKSMOBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119654324-A | Novel compounds as hypoxia inducible factor 1 (HIF-1) inhibitors or Vascular Endothelial Growth Factor (VEGF) inhibitors and pharmaceutical compositions comprising the same | 株式会社次代生物科学 | 2025-03-18 | — | — | CN | claimed |
| CN-119654324-A | Novel compounds as hypoxia inducible factor 1 (HIF-1) inhibitors or Vascular Endothelial Growth Factor (VEGF) inhibitors and pharmaceutical compositions comprising the same | 株式会社次代生物科学 | 2025-03-18 | — | — | CN | disclosed |