Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 4/20 | 0.37 |
| ▸ | SMO | Q99835 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | WDR5 | P61964 | 5/20 | 0.36 |
| ▸ | BTK | Q06187 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30751438 | 0.93 | GSK3B (0.39) | ADORA1TP53NR2E3 | |
| SCHEMBL27375170 | 0.92 | MET (0.37) | SMOBTKNR2E3 | |
| SCHEMBL30751355 | 0.92 | MET (0.37) | SMOBTKNR2E3 | |
| SCHEMBL27376866 | 0.91 | MET (0.37) | SMOBTKNR2E3 | |
| SCHEMBL31456927 | 0.91 | SMN1; SMN2 (0.39) | SMOADORA1BTK | |
| SCHEMBL27377070 | 0.91 | SMN1; SMN2 (0.39) | SMOADORA1BTK | |
| SCHEMBL27376939 | 0.90 | GRIN2B (0.38) | CCR1SMOADORA1BTKTP53 | |
| SCHEMBL31456924 | 0.90 | GRIN2B (0.38) | CCR1SMOADORA1BTKTP53 | |
| SCHEMBL30751430 | 0.89 | SMO (0.37) | SMOADORA1BTKNR2E3 | |
| SCHEMBL31456920 | 0.89 | SMO (0.37) | SMOBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119654324-A | Novel compounds as hypoxia inducible factor 1 (HIF-1) inhibitors or Vascular Endothelial Growth Factor (VEGF) inhibitors and pharmaceutical compositions comprising the same | 株式会社次代生物科学 | 2025-03-18 | — | — | CN | claimed |
| CN-119654324-A | Novel compounds as hypoxia inducible factor 1 (HIF-1) inhibitors or Vascular Endothelial Growth Factor (VEGF) inhibitors and pharmaceutical compositions comprising the same | 株式会社次代生物科学 | 2025-03-18 | — | — | CN | disclosed |
| WO-2024030000-A1 | NOVEL COMPOUND AS HYPOXIA-INDUCIBLE FACTOR 1(HIF-1) INHIBITOR OR VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 넥스트젠바이오사이언스 | 2024-02-08 | — | — | WO | disclosed |