Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | CAMK1D | Q8IU85 | 17/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30751538 | 0.91 | PTPN11 (0.49) | SYKPTPN11PDE4BCAMK1D | |
| SCHEMBL30751519 | 0.88 | SYK (0.56) | SYKPDE4BCAMK1D | |
| SCHEMBL31673049 | 0.85 | CAMK1D (0.59) | PDE4BCAMK1D | |
| SCHEMBL30751499 | 0.85 | GPR119 (0.46) | SYKCAMK1D | |
| SCHEMBL30751511 | 0.80 | PTPN11 (0.53) | SYKPTPN11PDE4BCAMK1D | |
| SCHEMBL31673029 | 0.80 | CAMK1D (0.53) | SYKPDE4BCAMK1D | |
| SCHEMBL30751509 | 0.79 | SYK (0.46) | SYKPTPN11CAMK1D | |
| Hydrochloric Acid SCHEMBL31673023 | 0.79 | CAMK1D (0.53) | SYKPDE4BCAMK1D | |
| SCHEMBL31673036 | 0.78 | SYK (0.52) | SYKPDE4BCAMK1D | |
| SCHEMBL30751544 | 0.78 | PTPN11 (0.52) | SYKPTPN11PDE4BCAMK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250257051-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AS TYK2 INHIBITORS | 1910 GENETICS INC (US) | 2025-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250257051-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AS TYK2 INHIBITORS | TYK2, PDXK, JAK1 | SYK 201/4885PTPN11 535/4885PDE4B 4049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.