Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | GAA | P10253 | 8/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | CCR6 | P51684 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CSF1R | P07333 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1439589 | 1.00 | ALDH1A1 (0.71) | ALDH1A1GAAL3MBTL1SMN1; SMN2LMNA | |
| Nitrobenzene SCHEMBL28169097 | 0.81 | GAA (0.67) | ALDH1A1GAAL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL9965533 | 0.81 | GAA (0.53) | GAAL3MBTL1LMNAMAPTCYP2D6 | |
| SCHEMBL14704102 | 0.80 | GAA (0.53) | ALDH1A1GAASMN1; SMN2MAPTKMT2A | |
| SCHEMBL12582512 | 0.80 | GAA (0.62) | ALDH1A1GAAL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL3882416 | 0.78 | MAPT (0.69) | ALDH1A1GAASMN1; SMN2LMNAMAPT | |
| SCHEMBL4430377 | 0.77 | KMT2A (0.66) | ALDH1A1GAAL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL3888640 | 0.77 | MAPT (0.68) | ALDH1A1GAASMN1; SMN2LMNAHPGD | |
| Hydrochloric Acid SCHEMBL4047258 | 0.77 | MAPT (0.68) | ALDH1A1GAASMN1; SMN2LMNAMAPT | |
| SCHEMBL4962169 | 0.75 | MAPT (0.51) | ALDH1A1GAALMNAALOX12MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112300172-B | Bruton tyrosine kinase inhibitors | 比奥根MA公司 | 2024-01-16 | — | — | CN | disclosed |