Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.50 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30752017 | 0.81 | ALDH1A1 (0.71) | GAAKMT2ANPSR1L3MBTL1MAPT | |
| SCHEMBL1439589 | 0.81 | ALDH1A1 (0.71) | GAAKMT2ANPSR1L3MBTL1MAPT | |
| SCHEMBL13763656 | 0.76 | NPSR1 (0.65) | GAAKMT2ANPSR1KCNQ2L3MBTL1 | |
| SCHEMBL28236257 | 0.72 | ALDH1A1 (0.66) | GAAKMT2AMAPTTSHRCYP1A2 | |
| SCHEMBL1439619 | 0.72 | GAA (0.63) | GAAKMT2ANPSR1KCNQ2L3MBTL1 | |
| SCHEMBL4318899 | 0.72 | KCNQ2 (0.68) | GAAKMT2ANPSR1KCNQ2L3MBTL1 | |
| SCHEMBL9051602 | 0.71 | NPSR1 (0.63) | GAAKMT2ANPSR1KCNQ2L3MBTL1 | |
| SCHEMBL13757457 | 0.71 | GAA (0.61) | GAAKMT2ANPSR1KCNQ2L3MBTL1 | |
| SCHEMBL10144751 | 0.70 | L3MBTL1 (0.66) | GAAKMT2ANPSR1KCNQ2L3MBTL1 | |
| SCHEMBL6942726 | 0.70 | ALDH1A1 (0.49) | GAAKMT2ANPSR1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120157443-A1 | BRUTON'S TYROSINE KINASE INHIBITORS | SUNESIS PHARMACEUTICALS, INC. (US) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157443-A1 | BRUTON'S TYROSINE KINASE INHIBITORS | BTK, ABL1, SYK | GAA 1670/4885KMT2A 1481/4885NPSR1 4436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.