Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 7/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16598336 | 0.79 | TDP1 (0.39) | TDP1LMNA | |
| SCHEMBL105936 | 0.78 | ALDH1A1 (0.50) | TDP1ALDH1A1LMNARAB9AL3MBTL1 | |
| SCHEMBL18412050 | 0.76 | — | — | |
| SCHEMBL30973437 | 0.74 | TDP1 (0.38) | TDP1ALDH1A1LMNARAB9AL3MBTL1 | |
| SCHEMBL354023 | 0.71 | ALDH1A1 (0.44) | TDP1ALDH1A1LMNARAB9AL3MBTL1 | |
| SCHEMBL30833982 | 0.71 | ALDH1A1 (0.44) | TDP1ALDH1A1LMNARAB9AL3MBTL1 | |
| SCHEMBL29412881 | 0.71 | KEAP1 (0.48) | TDP1ALDH1A1LMNARAB9AL3MBTL1 | |
| SCHEMBL104396 | 0.71 | KEAP1 (0.48) | TDP1ALDH1A1LMNARAB9AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL6331781 | 0.70 | KEAP1 (0.47) | TDP1ALDH1A1LMNARAB9AL3MBTL1 | |
| SCHEMBL669037 | 0.70 | CASP1 (0.56) | TDP1ALDH1A1LMNARAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4719386-A2 | 5,6 SATURATED BICYCLIC HETEROCYLES USEFUL AS INHIBITORS OF NOD-LIKE RECEPTOR PROTEIN 3 | Merck Sharp & Dohme LLC (US) | 2026-04-08 | — | — | EP | disclosed |
| EP-4656635-A1 | SUBSTITUTED BENZENE COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2025-12-03 | — | — | EP | disclosed |
| EP-4568965-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF CANCER | F. Hoffmann-La Roche AG (CH) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024249389-A2 | 5,6 SATURATED BICYCLIC HETEROCYLES USEFUL AS INHIBITORS OF NOD-LIKE RECEPTOR PROTEIN 3 | MERCK SHARP & DOHME LLC (US) | 2024-12-05 | — | — | WO | disclosed |
| WO-2024157953-A1 | SUBSTITUTED BENZENE COMPOUND | 第一三共株式会社 | 2024-08-02 | — | — | WO | disclosed |
| WO-2024033454-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2024-02-15 | — | — | WO | disclosed |