SCHEMBL9066514

SCHEMBL9066514

C[Si](C)(Cl)CCCC(=O)Cl

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
TP53 P04637 1/20 0.50
TSHR P16473 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21877825 0.91 TSHR (0.54) ALDH1A1TP53TSHR
SCHEMBL10894480 0.85 ALDH1A1 (0.50) ALDH1A1TP53TSHR
SCHEMBL11205937 0.82 ALDH1A1 (0.52) ALDH1A1TP53TSHR
SCHEMBL11151060 0.82 ALDH1A1 (0.52) ALDH1A1TP53TSHR
SCHEMBL29082624 0.80 ALDH1A1 (0.43) ALDH1A1
SCHEMBL18227175 0.80 LMNA (0.48) ALDH1A1TSHR
SCHEMBL3798618 0.79 ALDH1A1 (0.48) ALDH1A1TP53TSHR
Hydrochloric Acid SCHEMBL9182562 0.78 LMNA (0.46) ALDH1A1TSHR
SCHEMBL11203798 0.76 ALDH1A1 (0.52) ALDH1A1TP53TSHR
SCHEMBL9356554 0.76 ALDH1A1 (0.46) ALDH1A1TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0499407-B1 Crosslinkers and chain extenders for room temperature vulcanization or crosslinking of polymers DOW CORNING (US) 1996-10-02 EP disclosed
EP-0499408-B1 Allyl cyclosilalactams DOW CORNING (US) 1995-05-17 EP disclosed
EP-0499408-A1 Allyl cyclosilalactams DOW CORNING CORPORATION (US) 1992-08-19 EP disclosed
EP-0499407-A1 Crosslinkers and chain extenders for room temperature vulcanization or crosslinking of polymers DOW CORNING CORPORATION (US) 1992-08-19 EP disclosed
US-5110967-A No evolution of volatile by-products; sealants DOW CORNING CORPORATION (US) 1992-05-05 US disclosed
US-5049688-A Allyl cyclosilalactams DOW CORNING CORPORATION (US) 1991-09-17 US disclosed