Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | F12 | P00748 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.35 |
| ▸ | SKP1 | P63208 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25336741 | 0.92 | MEN1 (0.38) | ADORA1NR1H2ESR2USP2SMN1; SMN2 | |
| SCHEMBL30752642 | 0.87 | NR1H2 (0.47) | ADORA1NR1H2ESR2USP2SMN1; SMN2 | |
| SCHEMBL30752551 | 0.86 | GPR119 (0.37) | NR1H2ESR2USP2SMN1; SMN2F12 | |
| SCHEMBL25338426 | 0.80 | NR1H2 (0.43) | ADORA1NR1H2ESR2USP2SMN1; SMN2 | |
| SCHEMBL30339167 | 0.80 | HTT (0.41) | ADORA1NR1H2ESR2USP2SMN1; SMN2 | |
| SCHEMBL30793677 | 0.80 | MEN1 (0.38) | ADORA1NR1H2ESR2USP2SMN1; SMN2 | |
| SCHEMBL25337124 | 0.79 | KMT2A (0.36) | NR1H2ESR2USP2SMN1; SMN2LMNA | |
| SCHEMBL24535150 | 0.79 | GPR119 (0.36) | NR1H2ESR2USP2SMN1; SMN2F12 | |
| SCHEMBL25335687 | 0.79 | MEN1 (0.43) | ADORA1NR1H2ESR2USP2SMN1; SMN2 | |
| SCHEMBL30793460 | 0.79 | MEN1 (0.38) | ADORA1NR1H2ESR2USP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565579-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF KRAS | Theras, Inc. (US) | 2025-06-11 | — | — | EP | disclosed |