Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.33 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 6/20 | 0.32 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.32 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31388140 | 0.82 | PGR (0.36) | ACACBKCNJ1KCNH2ARTRPV4 | |
| SCHEMBL31388102 | 0.78 | TBK1 (0.38) | KCNJ1KCNH2TBK1IKBKE | |
| SCHEMBL25400457 | 0.74 | BCL2A1 (0.45) | ARCYP2D6SLC6A2SLC6A4NOS2 | |
| SCHEMBL30430517 | 0.74 | BCL2A1 (0.45) | ARCYP2D6SLC6A2SLC6A4NOS2 | |
| SCHEMBL31535180 | 0.74 | KCNJ1 (0.34) | KCNJ1KCNH2ARTBK1TRPV4 | |
| SCHEMBL31506681 | 0.72 | AR (0.33) | ACACBKCNJ1KCNH2ARTRPV4 | |
| SCHEMBL31506682 | 0.72 | AR (0.33) | ACACBKCNJ1KCNH2ARTRPV4 | |
| SCHEMBL31506657 | 0.71 | AR (0.33) | ACACBKCNJ1KCNH2ARTRPV4 | |
| SCHEMBL19175421 | 0.71 | TRPV4 (0.37) | ARTRPV4 | |
| SCHEMBL31432493 | 0.70 | AR (0.40) | ACACBARTBK1IKBKETRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585261-A | PRMT5 inhibitor, preparation method and application thereof | 上海艾力斯医药科技股份有限公司 | 2025-03-07 | — | — | CN | disclosed |
| WO-2024027703-A1 | PRMT5 INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海艾力斯医药科技股份有限公司 | 2024-02-08 | — | — | WO | disclosed |