Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.35 |
| ▸ | EEF2K | O00418 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | PRKX | P51817 | 1/20 | 0.35 |
| ▸ | NEK4 | P51957 | 1/20 | 0.35 |
| ▸ | PRKG2 | Q13237 | 1/20 | 0.35 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21431482 | 0.83 | CYP11B2 (0.44) | ELANECYP11B2DTYMKKDM4E | |
| SCHEMBL31690642 | 0.83 | CYP11B2 (0.44) | ELANECYP11B2DTYMKKDM4E | |
| SCHEMBL30070345 | 0.82 | ELANE (0.40) | ELANEGPR119GBA1ROCK2ROCK1 | |
| SCHEMBL30854946 | 0.79 | EGFR (0.41) | ELANEGPR119CYP11B2ROCK2ROCK1 | |
| SCHEMBL8428527 | 0.72 | FGFR1 (0.44) | ELANEGPR119EGFRITKDTYMK | |
| SCHEMBL29640851 | 0.72 | FGFR1 (0.44) | ELANEGPR119EGFRITKDTYMK | |
| SCHEMBL22251171 | 0.70 | ELANE (0.40) | ELANEGPR119NAMPT | |
| SCHEMBL30343304 | 0.70 | GABRG2 (0.38) | ELANEGPR119GBA1KDM4E | |
| SCHEMBL31618416 | 0.70 | KDM4E (0.44) | ELANEKDM4E | |
| SCHEMBL2363023 | 0.70 | ELANE (0.49) | ELANEROCK2ROCK1CHEK2PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585261-A | PRMT5 inhibitor, preparation method and application thereof | 上海艾力斯医药科技股份有限公司 | 2025-03-07 | — | — | CN | disclosed |
| WO-2024027703-A1 | PRMT5 INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海艾力斯医药科技股份有限公司 | 2024-02-08 | — | — | WO | disclosed |