Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | PDE1A | P54750 | 1/20 | 0.41 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30752986 | 0.93 | ADORA1 (0.43) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL30752917 | 0.90 | ADORA1 (0.32) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL31496890 | 0.82 | ADORA1 (0.38) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL30753040 | 0.71 | PDPK1 (0.31) | PRMT5WDR77 | |
| SCHEMBL31496868 | 0.69 | ADORA1 (0.43) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL31388100 | 0.68 | ADORA1 (0.44) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL30753025 | 0.68 | PRMT5 (0.47) | PRMT5WDR77 | |
| SCHEMBL30752868 | 0.66 | PDE3B (0.40) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL25581275 | 0.66 | ADORA1 (0.38) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL30752860 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585261-A | PRMT5 inhibitor, preparation method and application thereof | 上海艾力斯医药科技股份有限公司 | 2025-03-07 | — | — | CN | disclosed |
| WO-2024027703-A1 | PRMT5 INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海艾力斯医药科技股份有限公司 | 2024-02-08 | — | — | WO | disclosed |