Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31496962 | 0.72 | KDM4A (0.31) | — | |
| SCHEMBL30752835 | 0.71 | ADORA1 (0.41) | PRMT5WDR77 | |
| SCHEMBL30752917 | 0.70 | ADORA1 (0.32) | — | |
| SCHEMBL30753025 | 0.65 | PRMT5 (0.47) | PRMT5WDR77 | |
| SCHEMBL30752986 | 0.64 | ADORA1 (0.43) | PRMT5WDR77 | |
| SCHEMBL31261075 | 0.61 | — | — | |
| SCHEMBL31168642 | 0.60 | PAX8 (0.34) | — | |
| SCHEMBL24150510 | 0.60 | MAP2K4 (0.40) | — | |
| SCHEMBL30379864 | 0.60 | MAP2K4 (0.40) | — | |
| SCHEMBL24035217 | 0.59 | MAPK14 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024027703-A1 | PRMT5 INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海艾力斯医药科技股份有限公司 | 2024-02-08 | — | — | WO | disclosed |