SCHEMBL30753146

SCHEMBL30753146

C[C@@H](O)[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 11/20 0.52
▸ OPRM1 P35372 10/20 0.52
▸ OPRK1 P41145 4/20 0.48
▸ PRMT1 Q99873 1/20 0.47
▸ GLP1R P43220 3/20 0.42
▸ SCTR P47872 1/20 0.42
▸ OPRL1 P41146 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30974312 0.91 OPRD1 (0.63) OPRD1OPRM1OPRK1GLP1RSCTR
SCHEMBL30090381 0.90 OPRD1 (0.57) OPRD1OPRM1OPRK1GLP1RSCTR
SCHEMBL30712882 0.89 OPRM1 (0.59) OPRD1OPRM1OPRK1GLP1RSCTR
SCHEMBL31253154 0.88 GLP1R (0.45) OPRD1OPRM1OPRK1PRMT1GLP1R
SCHEMBL31039959 0.88 MME (0.45) OPRD1OPRM1
SCHEMBL30637757 0.87 GLP1R (0.53) OPRD1OPRM1OPRK1GLP1RSCTR
SCHEMBL29375435 0.87 GLP1R (0.51) OPRD1OPRM1OPRK1GLP1RSCTR
SCHEMBL31094626 0.86 GLP1R (0.56) OPRD1PRMT1GLP1R
SCHEMBL29411293 0.86 PRMT1 (0.40) OPRD1OPRM1OPRK1PRMT1GLP1R
SCHEMBL29649733 0.84 OPRD1 (0.49) OPRD1OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11850285-B2 Insulin-responsive glucagon delivery patch NORTH CAROLINA STATE UNIVERSITY (US) 2023-12-26 — — US disclosed
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