SCHEMBL3075366

SCHEMBL3075366

CC(C)=CCOC(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
BTN3A1 O00481 1/20 0.35
MAPK1 P28482 1/20 0.35
GGPS1 O95749 1/20 0.34
ALOX15 P16050 2/20 0.33
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11573577 0.86 BTN3A1 (0.37) BTN3A1GGPS1ALOX15ALDH1A1
SCHEMBL16406011 0.80 GGPS1 (0.57) GGPS1ALOX15ALDH1A1
SCHEMBL24627649 0.80 GGPS1 (0.57) GGPS1ALOX15ALDH1A1
SCHEMBL14828668 0.77 GGPS1 (0.32) MAPK1GGPS1
SCHEMBL11123978 0.77 BTN3A1 (0.32) BTN3A1GGPS1ALOX15ALDH1A1
SCHEMBL11755129 0.75 GGPS1 (0.31) MAPK1GGPS1
SCHEMBL11755121 0.75 GGPS1 (0.31) MAPK1GGPS1
SCHEMBL9369217 0.75 ALOX15 (0.42) BTN3A1GGPS1ALOX15
SCHEMBL11141187 0.75 GGPS1 (0.34) BTN3A1GGPS1ALOX15ALDH1A1
SCHEMBL9796634 0.75 BTN3A1 (0.31) BTN3A1GGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109476640-A Bicyclic proline compounds 豪夫迈·罗氏有限公司 2019-03-15 CN disclosed
US-20180105749-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-04-19 US disclosed
US-20180057742-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-03-01 US disclosed
US-9868906-B2 Liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2018-01-16 US disclosed
US-20180002605-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-01-04 US disclosed
US-9562190-B2 Liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2017-02-07 US disclosed
US-20160168463-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2016-06-16 US disclosed
US-20160108314-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2016-04-21 US disclosed
US-9278989-B2 Sugar-derived gelator KYUSHU UNIVERSITY (JP) 2016-03-08 US disclosed
US-9131719-B2 Use of certain neoflavonoids for intensifying and/or producing a sensory impression of sweetness SYMRISE AG (DE) 2015-09-15 US disclosed
US-7705165-B2 Method for producing optically active cyclopropanecarboxylate compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-27 US disclosed
US-7671210-B2 Process for production of optically active cyclopropanecarboxylate compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
EP-1783130-B1 METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND SUMITOMO CHEMICAL CO (JP) 2009-12-30 EP disclosed
US-20090048450-A1 Process for production of optically active cyclopropanecarboxylate compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-02-19 US disclosed
US-20080027235-A1 Method for Producing Optically Active Cyclopropanecarboxylate Compound SUMITOMO CHEMICAL COMPANY, LIMITED 2008-01-31 US disclosed
EP-1783111-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND Sumitomo Chemical Company, Limited (JP) 2007-05-09 EP disclosed
EP-1783130-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND Sumitomo Chemical Company, Limited (JP) 2007-05-09 EP disclosed
US-20070032659-A1 Process for producing optically active cyclopropane compound and asymmetric copper complex for use in the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-02-08 US disclosed
CN-1852887-A Process for producing optically active cyclopropane compound and asymmetric copper complex for use in the same SUMITOMO CHEMICAL CO (JP) 2006-10-25 CN disclosed
EP-1674445-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE COMPOUND AND ASYMMETRIC COPPER COMPLEX FOR USE IN THE SAME Sumitomo Chemical Company, Limited (JP) 2006-06-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080027235-A1 Method for Producing Optically Active Cyclopropanecarboxylate Compound ACSL6, AOC1, CA6 BTN3A1 1832/4885MAPK1 3759/4885GGPS1 2040/4885
US-20090048450-A1 Process for production of optically active cyclopropanecarboxylate compound CBR3, C9, CBR1 BTN3A1 295/4885MAPK1 3048/4885GGPS1 2986/4885
US-20160168463-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE NLK, NCAPD2, LASP1 BTN3A1 1409/4885MAPK1 2120/4885GGPS1 3398/4885
US-20070032659-A1 Process for producing optically active cyclopropane compound and asymmetric copper complex for use in the same CBR3, AOC3, CBR1 BTN3A1 2308/4885MAPK1 3205/4885GGPS1 2230/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.