SCHEMBL30754183

SCHEMBL30754183

Cc1cc(F)c(F)c(F)c1C

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.37
ACHE P22303 1/20 0.33
TUBB1 Q9H4B7 1/20 0.31
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6299270 1.00 RAPGEF4 (0.37) RAPGEF4ACHETUBB1CES2CES1
Pyrimidine SCHEMBL29012309 0.82
SCHEMBL13980078 0.82 ACHE (0.33) RAPGEF4ACHETUBB1
SCHEMBL13891480 0.82 RAPGEF4 (0.37) RAPGEF4ACHETUBB1CES2CES1
SCHEMBL172019 0.79 CA1 (0.35) RAPGEF4CES2CES1
SCHEMBL2604714 0.79 CYP3A4 (0.30) ACHE
SCHEMBL30567470 0.79 RAPGEF4 (0.38) RAPGEF4ACHECES2CES1POLB
SCHEMBL823681 0.79 RAPGEF4 (0.38) RAPGEF4ACHECES2CES1POLB
SCHEMBL13271001 0.78 ACHE (0.33) RAPGEF4ACHETUBB1
SCHEMBL11353076 0.77 RAPGEF4 (0.37) RAPGEF4ACHECES2CES1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112236421-B Pyrazole derivatives and pest control agents 组合化学工业株式会社 2023-12-26 CN disclosed