Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL823681 | 0.97 | RAPGEF4 (0.38) | RAPGEF4ACHECES2CES1POLB | |
| SCHEMBL30567470 | 0.97 | RAPGEF4 (0.38) | RAPGEF4ACHECES2CES1POLB | |
| Bromide SCHEMBL27721878 | 0.94 | RAPGEF4 (0.37) | RAPGEF4ACHECES2CES1POLB | |
| SCHEMBL11415517 | 0.81 | CYP3A4 (0.35) | RAPGEF4ACHEHDAC1HDAC6 | |
| SCHEMBL17772465 | 0.78 | RAPGEF4 (0.34) | RAPGEF4ACHE | |
| SCHEMBL23865484 | 0.77 | ACHE (0.33) | RAPGEF4ACHE | |
| SCHEMBL30754183 | 0.77 | RAPGEF4 (0.37) | RAPGEF4ACHECES2CES1POLB | |
| SCHEMBL5391101 | 0.77 | ACHE (0.33) | RAPGEF4ACHEHDAC1HDAC6 | |
| SCHEMBL6299270 | 0.77 | RAPGEF4 (0.37) | RAPGEF4ACHECES2CES1POLB | |
| SCHEMBL2508266 | 0.77 | RAPGEF4 (0.37) | RAPGEF4ACHECES2CES1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4260645-A | NONAQUEOUS SOLVENT, SILVER PERCHLORATE, KITS | CANADIAN PATENTS AND DEVELOPMENT LIMITED (CA) | 1981-04-07 | — | — | US | disclosed |