Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | GPR183 | P32249 | 2/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL752526 | 0.88 | POLB (0.62) | POLBLMNAGAAGPR183HSD11B1 | |
| SCHEMBL28819237 | 0.86 | YAP1 (0.65) | POLBLMNAGAAGPR183HSD11B1 | |
| SCHEMBL751755 | 0.84 | NPC1 (0.74) | POLBLMNAGAAGPR183HSD11B1 | |
| SCHEMBL751873 | 0.84 | POLB (0.58) | POLBLMNAGAAGPR183HSD11B1 | |
| SCHEMBL751874 | 0.83 | POLB (0.60) | POLBLMNAGAAGPR183HSD11B1 | |
| SCHEMBL12169384 | 0.83 | LMNA (0.65) | POLBLMNAGAAGPR183HSD11B1 | |
| SCHEMBL732936 | 0.82 | GAA (0.76) | POLBLMNAGAAGPR183HSD11B1 | |
| SCHEMBL30754624 | 0.82 | ALDH1A1 (0.69) | LMNAGAAGPR183ALDH1A1 | |
| SCHEMBL752834 | 0.82 | LMNA (0.63) | POLBLMNAGAAGPR183HSD11B1 | |
| SCHEMBL30754632 | 0.81 | ALDH1A1 (0.68) | LMNAGAAKMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720528-A | Oxadiazole sulfonamide compound containing pyrazole structure, and preparation method and application thereof | 贵州大学 | 2024-03-19 | — | — | CN | disclosed |