Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 11/20 | 0.81 |
| ▸ | PGR | P06401 | 7/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.63 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.63 |
| ▸ | AR | P10275 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.63 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.63 |
| ▸ | IL5 | P05113 | 1/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.63 |
| ▸ | MMP9 | P14780 | 1/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | THPO | P40225 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13912206 | 0.92 | NR3C1 (0.69) | NR3C1PGRCYP3A4HIF1AHSD17B10 | |
| SCHEMBL30315823 | 0.91 | NR3C1 (0.79) | NR3C1PGRCYP3A4HIF1AHSD17B10 | |
| Deflazacort SCHEMBL24497637 | 0.90 | NR3C1 (1.00) | NR3C1PGRCYP3A4HIF1AHSD17B10 | |
| Deflazacort SCHEMBL2598076 | 0.90 | NR3C1 (1.00) | NR3C1PGRCYP3A4HIF1AHSD17B10 | |
| Deflazacort SCHEMBL4018 | 0.90 | NR3C1 (1.00) | NR3C1PGRCYP3A4HIF1AHSD17B10 | |
| Deflazacort SCHEMBL4019 | 0.90 | NR3C1 (1.00) | NR3C1PGRCYP3A4HIF1AHSD17B10 | |
| Deflazacort SCHEMBL4259541 | 0.89 | NR3C1 (0.95) | NR3C1PGRCYP3A4HIF1AHSD17B10 | |
| Deflazacort SCHEMBL22502722 | 0.89 | NR3C1 (0.98) | NR3C1PGRCYP3A4HIF1AHSD17B10 | |
| Deflazacort SCHEMBL17941674 | 0.87 | NR3C1 (0.94) | NR3C1PGRCYP3A4HIF1AHSD17B10 | |
| Deflazacort SCHEMBL887173 | 0.87 | NR3C1 (0.84) | NR3C1PGRCYP3A4HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024015527-A1 | THERAPEUTIC COMBINATIONS OF DRUGS, COMPANION DIAGNOSTICS AND METHODS FOR DOSAGING AND USING THEM | BAYESIAN BIOTECH, LLC (US) | 2024-01-18 | — | — | WO | claimed |
| WO-2024015527-A1 | THERAPEUTIC COMBINATIONS OF DRUGS, COMPANION DIAGNOSTICS AND METHODS FOR DOSAGING AND USING THEM | BAYESIAN BIOTECH, LLC (US) | 2024-01-18 | — | — | WO | disclosed |