Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CA2 | P00918 | 6/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29250358 | 0.88 | ALDH1A1 (0.47) | ALDH1A1CA2CYP3A4TSHRTDP1 | |
| SCHEMBL4969138 | 0.87 | ALDH1A1 (0.45) | ALDH1A1CA2CYP3A4TSHRTDP1 | |
| SCHEMBL688748 | 0.82 | CA2 (0.41) | ALDH1A1CA2CYP3A4TSHRTDP1 | |
| SCHEMBL7635219 | 0.81 | CA2 (0.40) | ALDH1A1CA2CYP3A4TSHRTDP1 | |
| SCHEMBL5718430 | 0.79 | CA2 (0.47) | ALDH1A1CA2CYP3A4TSHRTDP1 | |
| SCHEMBL7635236 | 0.78 | CA2 (0.40) | ALDH1A1CA2CYP3A4TSHRTDP1 | |
| SCHEMBL743473 | 0.77 | CA2 (0.50) | ALDH1A1CA2CYP3A4TSHRTDP1 | |
| SCHEMBL2250569 | 0.77 | CA2 (0.50) | ALDH1A1CA2CYP3A4TSHRTDP1 | |
| SCHEMBL28501108 | 0.77 | CA2 (0.46) | ALDH1A1CA2CYP3A4TSHRTDP1 | |
| SCHEMBL453703 | 0.77 | CA2 (0.48) | ALDH1A1CA2CYP3A4TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010105123-A1 | VISION ENHANCING OPTICAL ARTICLES | TRANSITIONS OPTICAL, INC. (US) | 2010-09-16 | — | — | WO | disclosed |
| US-20100232003-A1 | VISION ENHANCING OPTICAL ARTICLES | TRANSITIONS OPTICAL, INC. (US) | 2010-09-16 | — | — | US | disclosed |
| US-20080187749-A1 | OPTICAL ELEMENT HAVING LIGHT INFLUENCING PROPERTY | PPG INDUSTRIES OHIO, INC. (US) | 2008-08-07 | — | — | US | disclosed |
| WO-2008088633-A1 | OPTICAL ELEMENT HAVING LIGHT INFLUENCING PROPERTY | PPG INDUSTRIES OHIO, INC. (US) | 2008-07-24 | — | — | WO | disclosed |
| US-6433043-B1 | EPOXIDE; AND NAPHTHOPYRAN, QUINOPYRAN, INDENONAPHTHOPYRAN, PHENANTHROPYRAN, BENZOPYRAN, FULGIDES, FULGIMIDES, AND/OR METAL DITHIOZONATE PHOTOCHROMIC COMPOUND; OPHTHALMIC LENSES | TRANSITIONS OPTICAL, INC. | 2002-08-13 | — | — | US | disclosed |