SCHEMBL7635236

SCHEMBL7635236

CCCCC(CC)CC(O)(CC(=O)O)C(O)=S

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.40
ALDH1A1 P00352 4/20 0.39
HSPD1 P10809 1/20 0.38
BLM P54132 1/20 0.38
HSPE1 P61604 1/20 0.38
TSHR P16473 3/20 0.37
CYP3A4 P08684 3/20 0.37
TDP1 Q9NUW8 2/20 0.37
ATM Q13315 1/20 0.37
MAPK1 P28482 1/20 0.37
MMP9 P14780 1/20 0.33
MMP8 P22894 1/20 0.33
MMP14 P50281 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7640654 0.87 ALDH1A1 (0.41) CA2ALDH1A1TSHRCYP3A4TDP1
SCHEMBL4969138 0.87 ALDH1A1 (0.45) CA2ALDH1A1HSPD1BLMHSPE1
SCHEMBL4125234 0.80 CYP3A4 (0.50) CA2ALDH1A1HSPD1BLMHSPE1
Glycolic Acid SCHEMBL3075595 0.78 ALDH1A1 (0.46) CA2ALDH1A1HSPD1BLMHSPE1
SCHEMBL29250358 0.76 ALDH1A1 (0.47) CA2ALDH1A1HSPD1BLMHSPE1
SCHEMBL44319 0.76 CA2 (0.47) CA2ALDH1A1HSPD1BLMHSPE1
SCHEMBL7635219 0.75 CA2 (0.40) CA2ALDH1A1HSPD1BLMHSPE1
SCHEMBL16389850 0.75 ALDH1A1 (0.45) CA2ALDH1A1TSHRCYP3A4TDP1
Ammonia Solution, Strong SCHEMBL16192514 0.74 CA2 (0.46) CA2ALDH1A1HSPD1BLMHSPE1
Ammonia Solution, Strong SCHEMBL16192510 0.74 CA2 (0.46) CA2ALDH1A1HSPD1BLMHSPE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6462116-B2 POLYVINYL CHLORIDE(PVC), OR OTHER HALOPOLYMERS; 2-MERCAPTOETHANOL AND ZINC BIS(2-ETHYLHEXYLTHIOGLYCOLATE) FOR EXAMPLE; ELIMINATES ZINC BURN DURING PROCESSING MORTON INTERNATIONAL, INC. 2002-10-08 US disclosed