Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.38 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.37 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31492952 | 0.81 | KDM4E (0.43) | ALDH1A1S1PR2KDM4EMEN1KMT2A | |
| SCHEMBL30756024 | 0.81 | KDM4E (0.43) | ALDH1A1S1PR2KDM4EMEN1KMT2A | |
| SCHEMBL1397623 | 0.78 | P2RX3 (0.38) | ALDH1A1NAPRTGPBAR1 | |
| SCHEMBL1552677 | 0.77 | KMT2A (0.41) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL29773884 | 0.77 | NAPRT (0.47) | ALDH1A1HPGDKDM4EKMT2ANAPRT | |
| SCHEMBL979398 | 0.77 | NAPRT (0.47) | ALDH1A1HPGDKDM4EKMT2ANAPRT | |
| SCHEMBL30964013 | 0.76 | GABRP (0.47) | ALDH1A1HPGDKDM4EKMT2ANAPRT | |
| SCHEMBL18068216 | 0.76 | GABRP (0.47) | ALDH1A1HPGDKDM4EKMT2ANAPRT | |
| SCHEMBL29411268 | 0.75 | ALDH1A1 (0.47) | ALDH1A1KDM4EMEN1KMT2ANAPRT | |
| SCHEMBL1300053 | 0.75 | ALDH1A1 (0.47) | ALDH1A1KDM4EMEN1KMT2ANAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4554938-A1 | TYROSINE KINASE 2 INHIBITORS AND USES THEREOF | Biogen MA Inc. (US) | 2025-05-21 | — | — | EP | disclosed |
| CN-119894879-A | Tyrosine kinase 2 inhibitors and uses thereof | 渤健马萨诸塞州股份有限公司 | 2025-04-25 | — | — | CN | disclosed |
| WO-2024015497-A1 | TYROSINE KINASE 2 INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2024-01-18 | — | — | WO | disclosed |