Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ASPH | Q12797 | 2/20 | 0.31 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.31 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.31 |
| ▸ | RBP4 | P02753 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30756644 | 0.84 | PIM1 (0.43) | MAP4K4CNR2PIM1PIM2XDH | |
| SCHEMBL32667253 | 0.81 | MAP4K4 (0.48) | MAP4K4CNR2PIM1PIM2XDH | |
| SCHEMBL32667108 | 0.80 | IRAK4 (0.39) | TSHRHSD17B10MAP4K4CNR2PIM1 | |
| SCHEMBL22262501 | 0.78 | XDH (0.49) | MAP4K4PIM1PIM2XDHSCN9A | |
| SCHEMBL31492972 | 0.76 | TSHR (0.41) | TSHRHSD17B10LCKFYNKDM4E | |
| SCHEMBL30755720 | 0.76 | AAK1 (0.36) | CNR2 | |
| SCHEMBL23535454 | 0.74 | TSHR (0.60) | TSHRHSD17B10LCKFYNKDM4E | |
| SCHEMBL30427170 | 0.74 | TSHR (0.60) | TSHRHSD17B10LCKFYNKDM4E | |
| SCHEMBL16333723 | 0.74 | LCK (0.55) | TSHRHSD17B10LCKFYNKDM4E | |
| SCHEMBL32667179 | 0.74 | PRKAB2 (0.40) | TSHRHSD17B10CNR2XDHSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4554938-A1 | TYROSINE KINASE 2 INHIBITORS AND USES THEREOF | Biogen MA Inc. (US) | 2025-05-21 | — | — | EP | disclosed |
| CN-119894879-A | Tyrosine kinase 2 inhibitors and uses thereof | 渤健马萨诸塞州股份有限公司 | 2025-04-25 | — | — | CN | disclosed |
| WO-2024015497-A1 | TYROSINE KINASE 2 INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2024-01-18 | — | — | WO | disclosed |