Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.30 |
| ▸ | TAF1L | Q8IZX4 | 1/20 | 0.30 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.30 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26688793 | 1.00 | MAPT (0.33) | MAPTTP53ALDH1A1POLBRXFP1 | |
| SCHEMBL26688799 | 0.92 | MAPT (0.33) | MAPTTP53ALDH1A1POLBRXFP1 | |
| SCHEMBL30757516 | 0.92 | MAPT (0.33) | MAPTTP53ALDH1A1POLBRXFP1 | |
| SCHEMBL5521669 | 0.87 | EDNRA (0.36) | MAPTTP53 | |
| SCHEMBL26688901 | 0.87 | TSHR (0.34) | MAPTALDH1A1POLBLMNATSHR | |
| SCHEMBL30757386 | 0.87 | TSHR (0.34) | MAPTALDH1A1POLBLMNATSHR | |
| SCHEMBL5529373 | 0.87 | RORC (0.36) | — | |
| SCHEMBL5530889 | 0.86 | EDNRA (0.38) | — | |
| SCHEMBL30757411 | 0.85 | MAPT (0.33) | MAPTTP53ALDH1A1POLBRXFP1 | |
| SCHEMBL26688914 | 0.85 | MAPT (0.33) | MAPTTP53ALDH1A1POLBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023224963-A1 | DUAL-ACTING ANGIOTENSIN AND ENDOTHELIN RECEPTOR ANTAGONISTS | ARIA PHARMACEUTICALS, INC. (US) | 2023-11-23 | — | — | WO | disclosed |