Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.45 |
| ▸ | MDM4 | O15151 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30758116 | 0.91 | PTPN1 (0.45) | PTPN1MDM4TP53 | |
| SCHEMBL29812486 | 0.91 | MDM4 (0.43) | PTPN1MDM4TP53 | |
| SCHEMBL18764578 | 0.90 | CASP3 (0.49) | PTPN1MDM4TP53 | |
| SCHEMBL29812711 | 0.90 | MDM4 (0.48) | PTPN1MDM4TP53 | |
| SCHEMBL29483556 | 0.90 | MDM4 (0.48) | PTPN1MDM4TP53 | |
| SCHEMBL29372762 | 0.89 | PTPN1 (0.50) | PTPN1MDM4TP53 | |
| SCHEMBL20545940 | 0.88 | MDM4 (0.45) | PTPN1MDM4TP53 | |
| SCHEMBL13424242 | 0.88 | PTPN1 (0.48) | PTPN1MDM4TP53 | |
| SCHEMBL2199171 | 0.87 | PTPN1 (0.44) | PTPN1MDM4TP53 | |
| SCHEMBL2199165 | 0.87 | PTPN1 (0.44) | PTPN1MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230416329-A1 | A PEPTIDE WITH DISULFIDE BONDS AND INHIBITORY ACTIVITY AGAINST SERINE PROTEASES, DERIVED HYBRID PEPTIDES THEREOF, AND USES THEREOF | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2023-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230416329-A1 | A PEPTIDE WITH DISULFIDE BONDS AND INHIBITORY ACTIVITY AGAINST SERINE PROTEASES, DERIVED HYBRID PEPTIDES THEREOF, AND USES THEREOF | VIP, SI, TMPRSS15 | PTPN1 2678/4885MDM4 4066/4885TP53 1459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.