SCHEMBL30759516

SCHEMBL30759516

COc1cc2c(cc1Br)-c1c(c(C(=O)O)nn1-c1cc(Cl)cc(Cl)c1)SC2

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ PTGS2 P35354 12/20 0.42
▸ PTGS1 P23219 7/20 0.42
▸ CYP1A2 P05177 2/20 0.33
▸ HIF1A Q16665 1/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ CCNA2 P20248 1/20 0.32
▸ CDK2 P24941 1/20 0.32
▸ CCNA1 P78396 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.31
▸ CYP3A4 P08684 1/20 0.31
▸ CYP2C9 P11712 1/20 0.31
▸ CYP2C19 P33261 1/20 0.31
▸ HTR2A P28223 1/20 0.31
▸ HTR2C P28335 1/20 0.31
▸ HTR2B P41595 1/20 0.31
▸ APP P05067 1/20 0.31
▸ MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27118042 1.00 PTGS2 (0.42) PTGS2PTGS1CYP1A2HIF1AMEN1
SCHEMBL30759630 0.88 L3MBTL1 (0.39) PTGS2PTGS1KMT2AL3MBTL1CCNA2
SCHEMBL27118041 0.88 L3MBTL1 (0.39) PTGS2PTGS1KMT2AL3MBTL1CCNA2
SCHEMBL27118151 0.86 PTGS2 (0.40) PTGS2PTGS1ALDH1A1HTR2AHTR2C
SCHEMBL30759633 0.86 PTGS2 (0.40) PTGS2PTGS1ALDH1A1HTR2AHTR2C
SCHEMBL30759577 0.82 CCNA2 (0.43) CYP1A2HIF1AMEN1KMT2AL3MBTL1
SCHEMBL27119370 0.82 CCNA2 (0.43) CYP1A2HIF1AMEN1KMT2AL3MBTL1
SCHEMBL27118754 0.82 CA12 (0.39) CYP1A2HIF1ACCNA2CDK2CCNA1
SCHEMBL30759519 0.81 GRM5 (0.36) PTGS2PTGS1KMT2A
SCHEMBL27118043 0.81 GRM5 (0.36) PTGS2PTGS1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF GEDEON RICHTER PLC (HU) 2026-01-08 — — US disclosed
EP-4577206-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF Celmatix Inc. (US) 2025-07-02 — — EP disclosed
WO-2024044778-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF CELMATIX INC. (US) 2024-02-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF FSHR, GNRHR, LHCGR PTGS2 2868/4885PTGS1 1711/4885CYP1A2 4060/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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