SCHEMBL30759552

SCHEMBL30759552

COC(=O)c1cc(OC)nc(-c2cc3c(cc2OC)CCc2c(C(=O)N(C)C(C)(C)C)nn(-c4cc(Cl)cc(Cl)c4)c2-3)c1

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ RAD52 P43351 1/20 0.37
▸ PDE7A Q13946 1/20 0.36
▸ PDE3A Q14432 1/20 0.36
▸ PDE10A Q9Y233 1/20 0.36
▸ ALDH1A1 P00352 2/20 0.32
▸ KDM4E B2RXH2 1/20 0.32
▸ IKBKB O14920 1/20 0.30
▸ POLB P06746 1/20 0.30
▸ MAPT P10636 1/20 0.30
▸ NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27124466 1.00 RAD52 (0.37) RAD52PDE7APDE3APDE10AALDH1A1
SCHEMBL27124690 0.93 PDE7A (0.36) RAD52PDE7APDE3APDE10AIKBKB
SCHEMBL30759613 0.88 PDE7A (0.33) PDE7APDE3APDE10AALDH1A1KDM4E
SCHEMBL30759546 0.88 PDE7A (0.34) PDE7APDE3APDE10AALDH1A1KDM4E
SCHEMBL27124747 0.88 PDE7A (0.34) PDE7APDE3APDE10AALDH1A1KDM4E
SCHEMBL27124676 0.88 PDE7A (0.33) PDE7APDE3APDE10AALDH1A1KDM4E
SCHEMBL30759598 0.84 RAD52 (0.38) RAD52PDE7APDE3APDE10AIKBKB
SCHEMBL27119523 0.84 RAD52 (0.38) RAD52PDE7APDE3APDE10AIKBKB
SCHEMBL30759622 0.81 PDE7A (0.40) RAD52PDE7APDE3APDE10AALDH1A1
SCHEMBL30759620 0.81 PDE7A (0.40) RAD52PDE7APDE3APDE10AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF GEDEON RICHTER PLC (HU) 2026-01-08 — — US disclosed
EP-4577206-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF Celmatix Inc. (US) 2025-07-02 — — EP disclosed
WO-2024044778-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF CELMATIX INC. (US) 2024-02-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF FSHR, GNRHR, LHCGR RAD52 3591/4885PDE7A 400/4885PDE3A 386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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