SCHEMBL30759546

SCHEMBL30759546

COC(=O)c1cc(OC)nc(-c2cc3c(cc2OC)CSc2c(C(=O)N(C)C(C)(C)C)nn(-c4cc(Cl)cc(Cl)c4)c2-3)c1

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ PDE7A Q13946 1/20 0.34
▸ PDE3A Q14432 1/20 0.34
▸ PDE10A Q9Y233 1/20 0.34
▸ PTGS2 P35354 3/20 0.33
▸ PTGS1 P23219 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27124747 1.00 PDE7A (0.34) PDE7APDE3APDE10APTGS2PTGS1
SCHEMBL27150953 0.94 PDE7A (0.35) PDE7APDE3APDE10APTGS2PTGS1
SCHEMBL27124748 0.93 PTGS2 (0.34) PDE7APDE3APDE10APTGS2PTGS1
SCHEMBL30759665 0.93 PTGS2 (0.34) PDE7APDE3APDE10APTGS2PTGS1
SCHEMBL30759552 0.88 RAD52 (0.37) PDE7APDE3APDE10AKDM4EALDH1A1
SCHEMBL27124466 0.88 RAD52 (0.37) PDE7APDE3APDE10AKDM4EALDH1A1
SCHEMBL30759613 0.86 PDE7A (0.33) PDE7APDE3APDE10AKDM4EALDH1A1
SCHEMBL27124676 0.86 PDE7A (0.33) PDE7APDE3APDE10AKDM4EALDH1A1
SCHEMBL27118272 0.84 PTGS2 (0.38) PDE7APDE3APDE10APTGS2PTGS1
SCHEMBL30759633 0.82 PTGS2 (0.40) PDE7APDE3APDE10APTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF GEDEON RICHTER PLC (HU) 2026-01-08 — — US disclosed
EP-4577206-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF Celmatix Inc. (US) 2025-07-02 — — EP disclosed
WO-2024044778-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF CELMATIX INC. (US) 2024-02-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF FSHR, GNRHR, LHCGR PDE7A 400/4885PDE3A 386/4885PDE10A 741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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