SCHEMBL30759598

SCHEMBL30759598

COc1cc2c(cc1-c1ccn(C)n1)-c1c(c(C(=O)N(C)C(C)(C)C)nn1-c1cc(Cl)cc(Cl)c1)CC2

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ RAD52 P43351 1/20 0.38
▸ PDE7A Q13946 1/20 0.37
▸ PDE3A Q14432 1/20 0.37
▸ PDE10A Q9Y233 1/20 0.37
▸ IKBKB O14920 11/20 0.34
▸ F10 P00742 1/20 0.31
▸ CCNA2 P20248 3/20 0.31
▸ CDK2 P24941 3/20 0.31
▸ CCNA1 P78396 3/20 0.31
▸ CNR1 P21554 1/20 0.31
▸ CNR2 P34972 1/20 0.31
▸ CHUK O15111 1/20 0.30
▸ CGAS Q8N884 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27119523 1.00 RAD52 (0.38) RAD52PDE7APDE3APDE10AIKBKB
SCHEMBL27118937 0.93 CA12 (0.36) RAD52PDE7APDE3APDE10AIKBKB
SCHEMBL27118272 0.86 PTGS2 (0.38) PDE7APDE3APDE10A
SCHEMBL27117946 0.86 PDE7A (0.34) PDE7APDE3APDE10A
SCHEMBL17381962 0.86 NR1H4 (0.38) —
SCHEMBL27119529 0.86 PDE7A (0.40) RAD52PDE7APDE3APDE10AIKBKB
SCHEMBL30759620 0.86 PDE7A (0.40) RAD52PDE7APDE3APDE10AIKBKB
SCHEMBL30759622 0.86 PDE7A (0.40) RAD52PDE7APDE3APDE10AIKBKB
SCHEMBL30759552 0.84 RAD52 (0.37) RAD52PDE7APDE3APDE10AIKBKB
SCHEMBL27124466 0.84 RAD52 (0.37) RAD52PDE7APDE3APDE10AIKBKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF GEDEON RICHTER PLC (HU) 2026-01-08 — — US disclosed
EP-4577206-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF Celmatix Inc. (US) 2025-07-02 — — EP disclosed
WO-2024044778-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF CELMATIX INC. (US) 2024-02-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF FSHR, GNRHR, LHCGR RAD52 3591/4885PDE7A 400/4885PDE3A 386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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