SCHEMBL30759665

SCHEMBL30759665

COc1cc(C(N)=O)cc(-c2cc3c(cc2OC)CSc2c(C(=O)N(C)C(C)(C)C)nn(-c4cc(Cl)cc(Cl)c4)c2-3)n1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ PTGS2 P35354 3/20 0.34
▸ PTGS1 P23219 1/20 0.34
▸ PDE7A Q13946 1/20 0.34
▸ PDE3A Q14432 1/20 0.34
▸ PDE10A Q9Y233 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27124748 1.00 PTGS2 (0.34) PTGS2PTGS1PDE7APDE3APDE10A
SCHEMBL27150953 0.94 PDE7A (0.35) PTGS2PTGS1PDE7APDE3APDE10A
SCHEMBL27124747 0.93 PDE7A (0.34) PTGS2PTGS1PDE7APDE3APDE10A
SCHEMBL30759546 0.93 PDE7A (0.34) PTGS2PTGS1PDE7APDE3APDE10A
SCHEMBL27124690 0.88 PDE7A (0.36) PDE7APDE3APDE10A
SCHEMBL30759589 0.86 PDE7A (0.33) PDE7APDE3APDE10A
SCHEMBL27124643 0.86 PDE7A (0.33) PDE7APDE3APDE10A
SCHEMBL30759559 0.85 PTGS2 (0.35) PTGS2PTGS1PDE7APDE3APDE10A
SCHEMBL27118239 0.85 PTGS2 (0.35) PTGS2PTGS1PDE7APDE3APDE10A
SCHEMBL27118272 0.84 PTGS2 (0.38) PTGS2PTGS1PDE7APDE3APDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF GEDEON RICHTER PLC (HU) 2026-01-08 — — US disclosed
EP-4577206-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF Celmatix Inc. (US) 2025-07-02 — — EP disclosed
WO-2024044778-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF CELMATIX INC. (US) 2024-02-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF FSHR, GNRHR, LHCGR PTGS2 2868/4885PTGS1 1711/4885PDE7A 400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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