Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 5/20 | 0.58 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.57 |
| ▸ | AHR | P35869 | 3/20 | 0.56 |
| ▸ | CMA1 | P23946 | 2/20 | 0.56 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.54 |
| ▸ | TDP2 | O95551 | 3/20 | 0.54 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3194345 | 1.00 | SMYD3 (0.58) | SMYD3CRBNAHRCMA1EIF2AK2 | |
| Hydrochloric Acid SCHEMBL29528151 | 0.98 | SMYD3 (0.57) | SMYD3CRBNAHRCMA1EIF2AK2 | |
| SCHEMBL3573876 | 0.90 | SMYD3 (0.56) | SMYD3CRBNAHRCMA1EIF2AK2 | |
| SCHEMBL3581639 | 0.89 | TDP2 (0.55) | SMYD3CRBNAHRCMA1EIF2AK2 | |
| SCHEMBL29567045 | 0.88 | SMYD3 (0.57) | SMYD3AHRTDP2HDAC3 | |
| SCHEMBL3190474 | 0.88 | SMYD3 (0.57) | SMYD3AHRTDP2HDAC3 | |
| Hydrochloric Acid SCHEMBL28849276 | 0.86 | SMYD3 (0.56) | SMYD3AHRTDP2HDAC3 | |
| SCHEMBL398818 | 0.86 | TDP2 (0.66) | SMYD3CRBNAHRCMA1EIF2AK2 | |
| SCHEMBL29713338 | 0.86 | TDP2 (0.66) | SMYD3CRBNAHRCMA1EIF2AK2 | |
| SCHEMBL29899565 | 0.85 | TDP2 (0.72) | SMYD3CRBNAHRCMA1TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117321418-A | Cancer biomarkers and methods of use thereof | 诺华股份有限公司 | 2023-12-29 | — | — | CN | disclosed |