SCHEMBL30762129

SCHEMBL30762129

Clc1cnc2c(ccc3ccccc32)n1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.44
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
MAPT P10636 3/20 0.42
LMNA P02545 3/20 0.42
RECQL P46063 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
PRMT5 O14744 1/20 0.41
PRMT3 O60678 1/20 0.41
CARM1 Q86X55 1/20 0.41
EHMT2 Q96KQ7 1/20 0.41
PRMT6 Q96LA8 1/20 0.41
PRMT1 Q99873 1/20 0.41
WDR77 Q9BQA1 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
APEX1 P27695 1/20 0.41
MAPK1 P28482 1/20 0.41
PMP22 Q01453 1/20 0.41
ALDH1A1 P00352 3/20 0.40
MEN1 O00255 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17532739 0.78 MAOA (0.45) CYP3A4NPC1RAB9AMAPTLMNA
SCHEMBL5470832 0.75 PRMT5 (0.56) CYP3A4NPC1RAB9AMAPTLMNA
SCHEMBL24596449 0.75 TLR9 (0.53) NPC1RAB9AMAPTLMNARECQL
SCHEMBL31326902 0.75 TDP1 (0.50) CYP3A4NPC1RAB9AMAPTLMNA
SCHEMBL19520619 0.75 TDP1 (0.50) CYP3A4NPC1RAB9AMAPTLMNA
SCHEMBL5473804 0.73 PRMT5 (0.59) CYP3A4NPC1RAB9AMAPTLMNA
SCHEMBL24596466 0.73 TLR9 (0.50) NPC1RAB9AMAPTLMNARECQL
SCHEMBL7689829 0.72 ALDH1A1 (0.61) NPC1RAB9AMAPTSMN1; SMN2L3MBTL1
SCHEMBL730579 0.72 CYP3A4 (0.61) CYP3A4NPC1RAB9AMAPTLMNA
SCHEMBL284801 0.72 ALDH1A1 (0.40) CYP3A4MAPTLMNAL3MBTL1APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112533912-B Compound and organic light emitting device comprising the same 株式会社LG化学 2024-01-02 CN disclosed