Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | NQO2 | P16083 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.37 |
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222284 | 0.79 | SMN1; SMN2 (0.53) | ALDH1A1CYP1A2MAPTNPC1PDGFRB | |
| SCHEMBL30731286 | 0.79 | SMN1; SMN2 (0.53) | ALDH1A1CYP1A2MAPTNPC1PDGFRB | |
| SCHEMBL2552603 | 0.79 | ALDH1A1 (0.68) | ALDH1A1NQO2PDGFRBHTTPDGFRA | |
| Hydrogen Sulfide SCHEMBL28270010 | 0.77 | SMN1; SMN2 (0.52) | ALDH1A1CYP1A2MAPTNPC1PDGFRB | |
| SCHEMBL1258994 | 0.76 | ALDH1A1 (0.63) | ALDH1A1MAPTPDGFRBPDGFRA | |
| SCHEMBL6216217 | 0.76 | ALDH1A1 (1.00) | ALDH1A1NQO2CYP1A2MAPTNPC1 | |
| SCHEMBL30775085 | 0.76 | ALDH1A1 (0.63) | ALDH1A1MAPTPDGFRBPDGFRA | |
| SCHEMBL28156588 | 0.75 | ALDH1A1 (0.47) | ALDH1A1NPC1PDGFRBRAB9ASMN1; SMN2 | |
| SCHEMBL23618588 | 0.74 | NQO2 (0.50) | ALDH1A1NQO2CYP1A2MAPTNPC1 | |
| SCHEMBL346120 | 0.74 | ALDH1A1 (0.55) | ALDH1A1CYP1A2MAPTNPC1PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | claimed |
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |