Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.59 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.52 |
| ▸ | PRKACA | P17612 | 3/20 | 0.50 |
| ▸ | PRKACG | P22612 | 3/20 | 0.50 |
| ▸ | PRKACB | P22694 | 3/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29278104 | 1.00 | MBTD1 (0.59) | MBTD1L3MBTL3SMN1; SMN2TDP1SLC18A3 | |
| SCHEMBL30762161 | 0.91 | SMN1; SMN2 (0.63) | MBTD1L3MBTL3SMN1; SMN2TDP1SLC18A3 | |
| SCHEMBL29278105 | 0.91 | SMN1; SMN2 (0.63) | MBTD1L3MBTL3SMN1; SMN2TDP1SLC18A3 | |
| SCHEMBL17967809 | 0.82 | BCHE (0.56) | PRKACAPRKACGPRKACBKMT2AKDM4E | |
| SCHEMBL21765824 | 0.82 | DRD2 (0.52) | PRKACAPRKACGPRKACBSIGMAR1KMT2A | |
| SCHEMBL30056809 | 0.82 | DRD2 (0.52) | PRKACAPRKACGPRKACBSIGMAR1KMT2A | |
| SCHEMBL4849913 | 0.81 | BCHE (0.54) | SIGMAR1DRD4KMT2AKDM4E | |
| SCHEMBL4849908 | 0.81 | BCHE (0.54) | SIGMAR1DRD4KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL30921645 | 0.81 | DRD2 (0.51) | PRKACAPRKACGPRKACBSIGMAR1KMT2A | |
| Hydrochloric Acid SCHEMBL21752840 | 0.81 | DRD2 (0.51) | PRKACAPRKACGPRKACBSIGMAR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117402081-A | Aryl substituted amine derivative, preparation method and application thereof | 南京医科大学 | 2024-01-16 | — | — | CN | disclosed |