Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31547997 | 0.81 | ROCK2 (0.45) | RXRARXRBROCK2GABRA1GABRG2 | |
| SCHEMBL2727228 | 0.75 | ROCK2 (0.49) | RXRARXRBROCK2GABRA1LMNA | |
| SCHEMBL2737262 | 0.75 | KDM4E (0.49) | RXRARXRBGABRA1GABRG2GABRB3 | |
| SCHEMBL30869371 | 0.75 | ROCK2 (0.50) | RXRARXRBROCK2GABRA1GABRG2 | |
| SCHEMBL29424818 | 0.73 | ROCK2 (0.48) | RXRARXRBROCK2GABRA1LMNA | |
| Phosphine SCHEMBL27043067 | 0.73 | ROCK2 (0.48) | RXRARXRBROCK2GABRA1LMNA | |
| SCHEMBL8469211 | 0.73 | RXRA (0.72) | RXRARXRBGABRA1GABRG2GABRB3 | |
| SCHEMBL30842176 | 0.73 | ROCK2 (0.48) | RXRARXRBROCK2GABRA1GABRG2 | |
| SCHEMBL2968363 | 0.72 | RXRA (0.53) | RXRARXRBGABRA1GABRG2GABRB3 | |
| SCHEMBL18210776 | 0.70 | RXRA (0.58) | RXRARXRBGABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067247-A1 | PREPARATION METHOD FOR ON-DNA AROMATIC COMPOUND, AND APPLICATION OF PREPARATION METHOD | 深圳晶泰科技有限公司 | 2025-04-03 | — | — | WO | claimed |
| CN-117364252-A | Preparation method and application of On-DNA aromatic compound | 深圳晶泰科技有限公司 | 2024-01-09 | — | — | CN | claimed |
| WO-2025067247-A1 | PREPARATION METHOD FOR ON-DNA AROMATIC COMPOUND, AND APPLICATION OF PREPARATION METHOD | 深圳晶泰科技有限公司 | 2025-04-03 | — | — | WO | disclosed |
| US-20240374588-A1 | IRAK4 PROTACS | ASTRAZENECA AB (SE) | 2024-11-14 | — | — | US | disclosed |
| WO-2024056005-A1 | POLYCYCLIC COMPOUND AND USE THEREOF | 先声再明医药有限公司 | 2024-03-21 | — | — | WO | disclosed |
| CN-117364252-A | Preparation method and application of On-DNA aromatic compound | 深圳晶泰科技有限公司 | 2024-01-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240374588-A1 | IRAK4 PROTACS | IRAK4, IRAK2, IRAK3 | RXRA 392/4885RXRB 306/4885ROCK2 2800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.