Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | FABP3 | P05413 | 2/20 | 0.35 |
| ▸ | FABP4 | P15090 | 2/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2727228 | 0.79 | ROCK2 (0.49) | ROCK2GABRA1GABRB2FABP3FABP4 | |
| Phosphine SCHEMBL27043067 | 0.77 | ROCK2 (0.48) | ROCK2GABRA1GABRB2FABP3FABP4 | |
| SCHEMBL29424818 | 0.77 | ROCK2 (0.48) | ROCK2GABRA1GABRB2FABP3FABP4 | |
| SCHEMBL30842176 | 0.76 | ROCK2 (0.48) | ROCK2GABRA1GABRB2FABP3FABP4 | |
| SCHEMBL30762275 | 0.75 | RXRA (0.48) | ROCK2GABRA1FABP3FABP4RXRA | |
| SCHEMBL30317598 | 0.74 | ROCK2 (0.39) | ROCK2GABRA1GABRB2FABP3FABP4 | |
| Carbimide SCHEMBL27867638 | 0.73 | ROCK2 (0.44) | ROCK2GABRA1GABRB2FABP3FABP4 | |
| Hydrochloric Acid SCHEMBL21331878 | 0.73 | ROCK2 (0.38) | ROCK2GABRA1GABRB2FABP3FABP4 | |
| SCHEMBL31547997 | 0.72 | ROCK2 (0.45) | ROCK2GABRA1GABRB2FABP3FABP4 | |
| SCHEMBL18150128 | 0.72 | ROCK2 (0.58) | ROCK2GABRA1GABRB2FABP3FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240174683-A1 | MAP4K1 INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2024-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240174683-A1 | MAP4K1 INHIBITORS | MAP3K4, MAP4K4, MAP4K1 | ROCK2 298/4885GABRA1 4662/4885GABRB2 4653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.