Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30762361 | 0.83 | ALDH1A1 (0.49) | ATML3MBTL1TDP1ACHEKMT2A | |
| SCHEMBL30762357 | 0.79 | ALDH1A1 (0.52) | ATML3MBTL1TDP1ACHEKMT2A | |
| SCHEMBL11739337 | 0.76 | ATM (0.70) | ATML3MBTL1TDP1ACHEKMT2A | |
| SCHEMBL21939660 | 0.73 | CYP1A2 (0.46) | L3MBTL1KMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL10587995 | 0.72 | ALDH1A1 (0.52) | ATML3MBTL1TDP1ACHEKMT2A | |
| SCHEMBL30762501 | 0.72 | KMT2A (0.57) | ATML3MBTL1TDP1ACHEKMT2A | |
| SCHEMBL11863517 | 0.72 | ALDH1A1 (0.52) | ATML3MBTL1TDP1ACHEKMT2A | |
| SCHEMBL17531151 | 0.71 | L3MBTL1 (0.71) | ATML3MBTL1TDP1ACHEKMT2A | |
| SCHEMBL14595182 | 0.71 | ALDH1A1 (0.65) | KMT2AMAPK1ALDH1A1KDM4EMEN1 | |
| SCHEMBL30762379 | 0.70 | ALDH1A1 (0.48) | ATMKMT2APOLBMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026423-A1 | SUBSTITUTED QUINOLINE DERIVATIVES AS PI3K INHIBITORS | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |