Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14044130 | 0.79 | CYP1A2 (0.72) | CYP1A2CYP2D6CYP2C9CYP2C19RXFP1 | |
| SCHEMBL10496106 | 0.78 | GPR3 (0.53) | CYP1A2CYP2D6CYP2C9CYP2C19RXFP1 | |
| SCHEMBL9724245 | 0.74 | LMNA (0.55) | CYP1A2CYP2D6CYP2C9CYP2C19RXFP1 | |
| SCHEMBL13107066 | 0.74 | KDM4E (0.49) | KDM4EPKMLMNAALDH1A1ELANE | |
| Hydrochloric Acid SCHEMBL27551107 | 0.73 | LMNA (0.53) | CYP1A2CYP2D6CYP2C9CYP2C19RXFP1 | |
| SCHEMBL30762600 | 0.73 | ATM (0.51) | CYP1A2CYP2C9KDM4ELMNAALDH1A1 | |
| SCHEMBL2124437 | 0.71 | KDM4E (0.46) | CYP1A2CYP2C9CYP2C19KDM4EPKM | |
| Hydrochloric Acid SCHEMBL12479363 | 0.71 | ACHE (0.43) | CYP1A2CYP2D6CYP2C9CYP2C19RXFP1 | |
| SCHEMBL13349883 | 0.71 | ALDH1A1 (0.43) | KDM4EPKMLMNAALDH1A1ELANE | |
| SCHEMBL21574677 | 0.71 | PKM (0.45) | CYP1A2CYP2D6CYP2C9CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200131144-A1 | AMINE OR (THIO)AMIDE CONTAINING LXR MODULATORS | PHENEX-FXR GMBH (DE) | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131144-A1 | AMINE OR (THIO)AMIDE CONTAINING LXR MODULATORS | NR1H2, NR1H3, NR1H4 | CYP1A2 292/4885CYP2D6 1206/4885CYP2C9 1006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.