Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10394797 | 0.88 | IDH1 (0.44) | CALM1CYP3A4TSHRPIK3CAALDH1A1 | |
| SCHEMBL3165405 | 0.88 | CALM1 (0.41) | CALM1CYP3A4TSHRALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL3291591 | 0.86 | CALM1 (0.39) | CALM1CYP3A4ALDH1A1NPSR1MAPT | |
| Bromide SCHEMBL8174311 | 0.86 | CALM1 (0.39) | CALM1CYP3A4TSHRALDH1A1NPSR1 | |
| SCHEMBL1498780 | 0.84 | CALM1 (0.55) | CALM1ALDH1A1MAPTGAAPOLB | |
| SCHEMBL10533565 | 0.83 | TP53 (0.39) | CALM1ALDH1A1NPSR1MAPTHPGD | |
| SCHEMBL2990081 | 0.83 | CYP3A4 (0.52) | CYP3A4TSHRPIK3CAALDH1A1USP2 | |
| SCHEMBL5426526 | 0.82 | IDH1 (0.45) | CALM1CYP3A4TSHRALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL2988167 | 0.82 | CYP3A4 (0.50) | CYP3A4TSHRPIK3CAALDH1A1POLB | |
| SCHEMBL2990519 | 0.81 | MAOB (0.44) | CYP3A4TSHRPIK3CAALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108690043-B | Quinoline derivatives and its preparation method and application | 东莞东阳光科研发有限公司 | 2019-10-18 | — | — | CN | disclosed |
| CN-108690043-A | Quinoline derivatives and its preparation method and application | 东莞东阳光科研发有限公司 | 2018-10-23 | — | — | CN | disclosed |
| US-RE41549-E1 | Dyes for keratin fibers, the dyes containing n-benzyl-p-phenylenediamine derivatives and novel n-benzyl-p-phenylenediamine derivatives | WELLA AG (DE) | 2010-08-24 | — | — | US | disclosed |
| US-7422609-B2 | Double para-phenylenediamines joined by an aromatic group for dyeing keratin fibers | L'OREAL S.A. (FR) | 2008-09-09 | — | — | US | disclosed |
| US-20070011824-A1 | Double para-phenylenediamines joined by an aromatic group for dyeing keratin fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| US-6689174-B2 | FOR OXIDATIVELY DYEING HUMAN HAIR | WELLA AKTIENGESELLSCHAFT (DE) | 2004-02-10 | — | — | US | disclosed |
| US-20020166181-A1 | N-benzyl-p-phenylenediamine-derivatives containing colouring agents for keratin fibres and novel n-benzyl-p-phenylenediamine-derivatives | CHASSOT LAURENT (CH) | 2002-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070011824-A1 | Double para-phenylenediamines joined by an aromatic group for dyeing keratin fibers | KRT18, CDC73, JUP | CALM1 2131/4885CYP3A4 1046/4885TSHR 4796/4885 |
| US-20020166181-A1 | N-benzyl-p-phenylenediamine-derivatives containing colouring agents for keratin fibres and novel n-benzyl-p-phenylenediamine-derivatives | KRT18, KPNB1, VIM | CALM1 439/4885CYP3A4 3372/4885TSHR 4852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.