Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30763539 | 0.87 | MMP13 (0.40) | KMT2A | |
| SCHEMBL30763568 | 0.87 | MMP13 (0.40) | KMT2A | |
| SCHEMBL16414751 | 0.81 | STAT3 (0.41) | STAT3KMT2AKDM4EALDH1A1PSMD10 | |
| SCHEMBL30763602 | 0.77 | STAT3 (0.40) | STAT3TSHRKMT2AKDM4EALDH1A1 | |
| SCHEMBL16414881 | 0.77 | CYP2D6 (0.45) | STAT3KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL23089207 | 0.76 | STAT3 (0.38) | STAT3KMT2AKDM4EALDH1A1PSMD10 | |
| SCHEMBL21063446 | 0.74 | STAT3 (0.42) | STAT3KMT2AALDH1A1PSMD10LMNA | |
| SCHEMBL25389881 | 0.71 | STAT3 (0.44) | STAT3TSHRKMT2AKDM4EALDH1A1 | |
| SCHEMBL23705651 | 0.71 | STAT3 (0.44) | STAT3TSHRKMT2AKDM4EALDH1A1 | |
| SCHEMBL23860161 | 0.71 | ALDH1A1 (0.44) | STAT3KMT2AKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568946-A1 | MACROCYCLIC BCL6 DEGRADERS | Dana-Farber Cancer Institute, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035688-A1 | MACROCYCLIC BCL6 DEGRADERS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-02-15 | — | — | WO | disclosed |