Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15745413 | 0.81 | ZDHHC20 (0.44) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| SCHEMBL5176139 | 0.81 | TSHR (0.39) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| SCHEMBL21128857 | 0.81 | ZDHHC20 (0.44) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| SCHEMBL5175654 | 0.81 | TSHR (0.39) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| SCHEMBL13296117 | 0.81 | ZDHHC20 (0.47) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| SCHEMBL15804310 | 0.81 | ZDHHC20 (0.44) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| SCHEMBL4859222 | 0.81 | TSHR (0.39) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| SCHEMBL23424203 | 0.78 | ZDHHC20 (0.49) | ALDH1A1ZDHHC20CASP1HCAR2 | |
| SCHEMBL21013140 | 0.78 | ZDHHC20 (0.49) | ALDH1A1ZDHHC20CASP1HCAR2 | |
| SCHEMBL30764070 | 0.76 | ZDHHC20 (0.55) | ZDHHC20HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912831-B2 | Hydroxyethylpyrrolidone ethacrylate/glycidyl ethacrylate copolymers | ISP INVESTMENTS LLC (US) | 2024-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11912831-B2 | Hydroxyethylpyrrolidone ethacrylate/glycidyl ethacrylate copolymers | MMAB, PCNA, HMBS | TSHR 4725/4885TP53 520/4885EGLN1 74/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.