SCHEMBL5175654

SCHEMBL5175654

CN(CCO)C(=O)/C=C\C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
TP53 P04637 1/20 0.39
EGLN1 Q9GZT9 1/20 0.39
EGLN3 Q9H6Z9 1/20 0.39
ALDH1A1 P00352 3/20 0.37
CHRNB2 P17787 1/20 0.37
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37
CHRNA4 P43681 1/20 0.37
ZDHHC20 Q5W0Z9 1/20 0.37
CASP1 P29466 1/20 0.35
ESR1 P03372 1/20 0.35
MAPT P10636 1/20 0.35
HCAR2 Q8TDS4 4/20 0.34
NPC1 O15118 2/20 0.33
CNR1 P21554 1/20 0.33
GAA P10253 1/20 0.33
KDM4E B2RXH2 2/20 0.32
HTT P42858 1/20 0.32
LSS P48449 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4859222 1.00 TSHR (0.39) TSHRTP53EGLN1EGLN3ALDH1A1
SCHEMBL5176139 1.00 TSHR (0.39) TSHRTP53EGLN1EGLN3ALDH1A1
SCHEMBL15804310 0.83 ZDHHC20 (0.44) TSHRTP53EGLN1EGLN3ALDH1A1
SCHEMBL13296117 0.83 ZDHHC20 (0.47) TSHRTP53EGLN1EGLN3ALDH1A1
SCHEMBL21128857 0.83 ZDHHC20 (0.44) TSHRTP53EGLN1EGLN3ALDH1A1
SCHEMBL15745413 0.83 ZDHHC20 (0.44) TSHRTP53EGLN1EGLN3ALDH1A1
SCHEMBL5175649 0.81 CHRNB2 (0.36) CHRNB2CHRNB4CHRNA3CHRNA4CASP1
SCHEMBL5176137 0.81 CHRNB2 (0.36) CHRNB2CHRNB4CHRNA3CHRNA4CASP1
SCHEMBL30764036 0.81 TSHR (0.38) TSHRTP53EGLN1EGLN3ALDH1A1
SCHEMBL5174647 0.80 CHRNB2 (0.38) CHRNB2CHRNB4CHRNA3CHRNA4CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1281516-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2007-12-19 EP disclosed
EP-1602481-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2007-05-30 EP disclosed
EP-1203659-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2006-05-17 EP disclosed
EP-1602481-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2005-12-07 EP disclosed
US-6951171-B2 Using graft polymer on etched or anodized aluminum substrate FUJI PHOTO FILM CO., LTD. (JP) 2005-10-04 US disclosed
EP-1371500-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2005-09-28 EP disclosed
US-6939658-B2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2005-09-06 US disclosed
EP-1048457-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2004-12-15 EP disclosed
US-6824946-B2 SUPPORT WITH HYDROPHILIC SURFACE HAVING AN IMAGE-FORMING LAYER CONTAINING A HYDROPHOBIC HIGH MOLECULAR COMPOUND WITH SALTS OF SULFONATES AND CARBOXYLS WITH IODONIUM, SULFONIUM OR DIAZONIUM IONS FUJI PHOTO FILM CO., LTD. (JP) 2004-11-30 US disclosed
EP-1031414-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2004-06-16 EP disclosed
EP-1281516-A2 Planographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2003-02-05 EP disclosed
US-6509132-B1 Comprises an ink-receptive image area for receiving ink during the printing process and a hydrophilic non-image area for receiving fountain solution FUJI PHOTO FILM CO., LTD. (JP) 2003-01-21 US disclosed
US-6455224-B1 SUPPORT WITH HYDROPHILIC SURFACE AND PHOTOSENSITIVE LAYER CONTAINING INFRARED ABSORBENT WHICH CHANGES FROM HYDROPHILIC TO HYDROPHOBIC BY HEAT AND HYDROPHILIC POLYMER HAVING FUNCTIONAL GROUP RENDERING LAYER WATER DEVELOPABLE FUJI PHOTO FILM CO., LTD. (JP) 2002-09-24 US disclosed
US-20020068241-A1 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2002-06-06 US disclosed
EP-1203659-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2002-05-08 EP disclosed
EP-1136281-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-09-26 EP disclosed
EP-1048457-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-11-02 EP disclosed
EP-1031414-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-08-30 EP disclosed
US-4212982-A Polyisocyanates with at least one hydantoin or thiohydantoin ring substituted by carboxylic acid amide groups BAYER AKTIENGESELLSCHAFT (DE) 1980-07-15 US disclosed
EP-0002445-A1 Polyiso(thio)cyanates wich contain hydantoin or thiohydantoin rings, their preparation and use BAYER AG (DE) 1979-06-27 EP disclosed