Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24151230 | 0.79 | ADRB2 (0.58) | NCF1MEN1GLAGAAKMT2A | |
| SCHEMBL3847734 | 0.78 | NCF1 (0.70) | NCF1MEN1GLAGAAKMT2A | |
| SCHEMBL3947682 | 0.78 | KDM4E (0.51) | NCF1MEN1GLAGAAKMT2A | |
| SCHEMBL12928129 | 0.78 | NCF1 (0.48) | NCF1MEN1GLAGAAKMT2A | |
| SCHEMBL13827009 | 0.78 | NCF1 (0.48) | NCF1MEN1GLAGAAKMT2A | |
| Hydrochloric Acid SCHEMBL7531114 | 0.77 | KDM4E (0.54) | NCF1MEN1GLAGAAKMT2A | |
| SCHEMBL7467872 | 0.75 | EIF2AK2 (0.55) | MEN1GAAKMT2ACYP3A4HRH3 | |
| SCHEMBL10268352 | 0.74 | NCF1 (0.67) | NCF1KMT2AKCNH2ADRB2METAP1 | |
| SCHEMBL16288863 | 0.72 | SMN1; SMN2 (0.46) | HTR1AHSD17B10MAPKAPK2 | |
| SCHEMBL4009656 | 0.71 | DYRK1B (0.39) | MEN1KMT2AHTR1AALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11884647-B2 | Compounds and methods for targeting pathogenic blood vessels | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-01-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11884647-B2 | Compounds and methods for targeting pathogenic blood vessels | TEK, KDR, LIPG | NCF1 974/4885MEN1 2514/4885GLA 1344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.