Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28820664 | 0.74 | ALDH1A1 (0.50) | ALDH1A1KDM4EGAAMAPTTSHR | |
| SCHEMBL1781741 | 0.73 | TSHR (0.46) | ALDH1A1KDM4EMAPTTSHRSMN1; SMN2 | |
| SCHEMBL929530 | 0.69 | TSHR (0.47) | ALDH1A1KDM4EGAAMAPTTSHR | |
| SCHEMBL19131345 | 0.69 | TSHR (0.39) | ALDH1A1KDM4EMAPTTSHRGRM5 | |
| SCHEMBL30764481 | 0.69 | TSHR (0.39) | ALDH1A1KDM4EMAPTTSHRMAPK1 | |
| SCHEMBL18237942 | 0.69 | TSHR (0.39) | ALDH1A1KDM4EMAPTTSHRSMN1; SMN2 | |
| SCHEMBL27168890 | 0.68 | TSHR (0.35) | ALDH1A1KDM4EGAAMAPTTSHR | |
| SCHEMBL30764525 | 0.68 | TSHR (0.35) | ALDH1A1KDM4EGAAMAPTTSHR | |
| SCHEMBL7917747 | 0.64 | TSHR (0.44) | ALDH1A1KDM4EMAPTTSHR | |
| SCHEMBL30667164 | 0.61 | CYP11B2 (0.40) | ALDH1A1TSHRGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117337290-A | Tri-ring ubiquitin-specific protease 1 inhibitors and uses thereof | 山东轩竹医药科技有限公司 | 2024-01-02 | — | — | CN | disclosed |