Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GHSR | Q92847 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MLNR | O43193 | 3/20 | 0.38 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ME2 | P23368 | 1/20 | 0.37 |
| ▸ | ME1 | P48163 | 1/20 | 0.37 |
| ▸ | ME3 | Q16798 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30764757 | 0.89 | HSD11B1 (0.46) | HSD11B1GHSRALDH1A1CHRM2SMN1; SMN2 | |
| SCHEMBL30764704 | 0.80 | KMT2A (0.54) | HSD11B1L3MBTL1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL30764750 | 0.76 | HSD11B1 (0.46) | HSD11B1L3MBTL1ALDH1A1POLBLMNA | |
| SCHEMBL30764701 | 0.76 | HSD11B1 (0.46) | HSD11B1L3MBTL1ALDH1A1POLBLMNA | |
| SCHEMBL30764706 | 0.76 | L3MBTL1 (0.57) | HSD11B1L3MBTL1GHSRALDH1A1LMNA | |
| SCHEMBL30764722 | 0.75 | HSD11B1 (0.46) | HSD11B1ALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL30764720 | 0.74 | SIGMAR1 (0.60) | HSD11B1L3MBTL1GHSRALDH1A1LMNA | |
| SCHEMBL30764733 | 0.74 | HSD11B1 (0.46) | HSD11B1L3MBTL1GHSRALDH1A1POLB | |
| SCHEMBL30764731 | 0.74 | HSD11B1 (0.56) | HSD11B1ALDH1A1POLBSMN1; SMN2ME2 | |
| SCHEMBL30764709 | 0.71 | HSD11B1 (0.53) | HSD11B1L3MBTL1ALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568968-A1 | (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | Remynd N.V. (BE) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024033479-A1 | (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | REMYND N.V. (BE) | 2024-02-15 | — | — | WO | disclosed |