Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 19/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 19/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16360885 | 1.00 | ESR1 (0.58) | ESR1ESR2HSP90AA1KDM4EALDH1A1 | |
| SCHEMBL15922141 | 0.79 | F9 (0.43) | ESR1ESR2KDM4EALDH1A1MAPT | |
| SCHEMBL2137945 | 0.79 | ESR1 (0.61) | ESR1ESR2HSP90AA1KDM4EALDH1A1 | |
| SCHEMBL8233882 | 0.76 | F9 (0.47) | ESR1ESR2KDM4EALDH1A1LMNA | |
| SCHEMBL1942334 | 0.76 | IDO1 (0.46) | ESR1ESR2HSP90AA1KDM4EHTT | |
| SCHEMBL24645496 | 0.76 | IDO1 (0.39) | ESR1ESR2HSP90AA1 | |
| SCHEMBL482377 | 0.76 | IDO1 (0.47) | ALDH1A1LMNAMAPTALOX15 | |
| SCHEMBL2440742 | 0.76 | ACHE (0.41) | ALDH1A1 | |
| SCHEMBL745847 | 0.76 | ESR1 (0.62) | ESR1ESR2HSP90AA1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL5109377 | 0.74 | IDO1 (0.46) | ALDH1A1LMNAMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112424181-B | Substituted condensed thiophenes as STING modulators | 希泰克斯特私人有限公司 | 2024-02-27 | — | — | CN | disclosed |