SCHEMBL482377

SCHEMBL482377

Nc1noc2cc(Cl)ccc12

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.47
ALDH1A1 P00352 1/20 0.45
KMT2A Q03164 1/20 0.45
PIK3CG P48736 1/20 0.43
AHR P35869 3/20 0.41
HTR3A P46098 3/20 0.40
CHRNA7 P36544 2/20 0.40
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
NR4A2 P43354 2/20 0.39
DAO P14920 1/20 0.39
LMNA P02545 1/20 0.39
CYP1A2 P05177 1/20 0.39
MAPT P10636 1/20 0.39
THRB P10828 1/20 0.39
ALOX15 P16050 1/20 0.39
MAPK1 P28482 1/20 0.39
SOS2 Q07890 1/20 0.39
AURKB Q96GD4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5109377 0.98 IDO1 (0.46) IDO1ALDH1A1KMT2APIK3CGAHR
SCHEMBL481909 0.84 IDO1 (0.50) IDO1ALDH1A1KMT2APIK3CGAHR
SCHEMBL30828709 0.84 IDO1 (0.50) IDO1ALDH1A1KMT2APIK3CGAHR
SCHEMBL7072970 0.80 MAP4K4 (0.46) IDO1CA1CA2
SCHEMBL1839676 0.79 ALDH1A1 (0.51) ALDH1A1KMT2APIK3CGAHRHTR3A
SCHEMBL15922141 0.79 F9 (0.43) IDO1ALDH1A1KMT2ACA1MAPT
SCHEMBL2438937 0.79 TLR7 (0.36) IDO1ALDH1A1KMT2AHTR3ACHRNA7
SCHEMBL27877404 0.78 ALDH1A1 (0.46) ALDH1A1KMT2APIK3CGAHRHTR3A
SCHEMBL24645496 0.76 IDO1 (0.39) IDO1AURKB
SCHEMBL30765144 0.76 ESR1 (0.58) ALDH1A1LMNAMAPTALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062393-A1 Compounds CTXT PTY LTD (AU) 2026-03-05 US disclosed
US-12365655-B2 Compounds CTXT PTY LTD (AU) 2025-07-22 US disclosed
CN-112334466-B Compounds of formula (I) CTXT私人有限公司 2025-05-30 CN disclosed
EP-4335439-A2 COMPOUNDS CTXT PTY LTD (AU) 2024-03-13 EP disclosed
EP-3810602-B1 COMPOUNDS CTXT PTY LTD (AU) 2023-11-01 EP disclosed
EP-3810602-B1 COMPOUNDS CTXT PTY LTD (AU) 2023-11-01 EP disclosed
US-20220153710-A1 Compounds CTXT PTY LTD (AU) 2022-05-19 US disclosed
US-20220153710-A1 Compounds CTXT PTY LTD (AU) 2022-05-19 US disclosed
US-20200039945-A1 Compounds CTXT PTY LIMITED (AU) 2020-02-06 US disclosed
US-20200039945-A1 Compounds CTXT PTY LIMITED (AU) 2020-02-06 US disclosed
US-5728717-A COGNITION ACTIVATORS, ANTIDEPRESSANTS HOECHST MARION ROUSSEL INC. (US) 1998-03-17 US disclosed
US-5668154-A TREATMENT OF MEMORY DYSFUNCTION, ALZHEIMER*S DISEASE, ANTIDEPRESSANTS HOECHST MARION ROUSSEL INC. (US) 1997-09-16 US disclosed
WO-1996039405-A1 PYRIDINIMINYL-1,2-BENZISOXAZOLES AND- BENZISOTHIAZOLES AS ANTIPSYCHOTIC AGENTS HOECHST MARION ROUSSEL, INC. (US) 1996-12-12 WO disclosed
US-5580982-A ANTIDEPRESSANTS; ANTICHOLINERGIC AGENTS; ALZHEIMER'S DISEASE; AMINE OXIDASE INHIBITORS HOECHST MARION ROUSSEL INC. (US) 1996-12-03 US disclosed
US-5494908-A ANTIDEPRESSANT HOECHST-ROUSSEL PHARMACEUTICAL INCORPORATED (US) 1996-02-27 US disclosed
EP-0669920-A4 SUBSTITUTED 3-(AMINOALKYLAMINO)-1,2-BENZISOXAZOLES AND RELATED COMPOUNDS. HOECHST ROUSSEL PHARMA (US) 1995-10-25 EP disclosed
EP-0669920-A1 SUBSTITUTED 3-(AMINOALKYLAMINO)-1,2-BENZISOXAZOLES AND RELATED COMPOUNDS HOECHST MARION ROUSSEL, Inc. (US) 1995-09-06 EP disclosed
US-5328920-A Alleviating memory dysfunctions HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1994-07-12 US disclosed
WO-1994012495-A1 SUBSTITUTED 3-(AMINOALKYLAMINO)-1,2-BENZISOXAZOLES AND RELATED COMPOUNDS HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1994-06-09 WO disclosed
EP-0594000-A1 Substituted (pyridinylamino)-benzisoxazoles and benzoisothiazole a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1994-04-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220153710-A1 Compounds SLC10A1, ABCB11, PCSK9 IDO1 3199/4885ALDH1A1 981/4885KMT2A 4165/4885
US-20200039945-A1 Compounds SLC10A1, ABCB11, PCSK9 IDO1 3200/4885ALDH1A1 982/4885KMT2A 4165/4885
US-20260062393-A1 Compounds SCN2B, ABCB11, SCN1B IDO1 3903/4885ALDH1A1 1864/4885KMT2A 890/4885
US-12365655-B2 Compounds SLC10A1, ABCB11, PCSK9 IDO1 3200/4885ALDH1A1 982/4885KMT2A 4165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.